Packed in the inert atmosphere

Protecting solid purple from light.
Packed in the inert atmosphere.

A less toxic, solid, synthetic derivatives of benzo-quinone ansamycin antibiotic Geldanamycin, Streptomyces hygroscopicus (Cat. No. 345805), based on Hsp90 (EC50 = 7.2 mm) and set the functions.

Induced apoptosis and showed anti-tumor effect (IC50 = 4.1 nm in SKBR3 and 5.2 nm in MCF7 cells). Out cancer cells erbB-1, erbB-2 (EC50 = 45 nm), mutant p53 (EC50 = 62 nm), Raf-1 (EC50 = 80 nm) and thus Akt inhibits the Ras / Raf / Mek and PI3-kinase signaling path. Read More